Duties & Responsibilities 

In this role you will:

You will be responsible for the curation of biological data in the ChEMBL database.

Reporting to the ChEMBL team coordinator, the job responsibilities will include:

• To work together with the other members of the ChEMBL data team to curate bioactivity data in the ChEMBL database ensuring the delivery of high quality data
• To map measured bioactivity data from the scientific literature to other biological entities (proteins, cell-lines etc) using a variety of bioinformatics resources and ontologies
• To identify and validate the potential therapeutic targets of drug molecules and compounds in clinical development from a variety of sources
• To work with data depositors to help them format and curate their data to the standards required for deposition into ChEMBL
• To manually check and annotate data by reference to the original data sources such as the scientific literature, Pharma Company pipelines and prescribing information
• To develop semi-automated processes for identifying and correcting erroneous data
• To be actively involved in training and external user support
• To work with other team members to publish project outcomes in scientific articles in the peer-reviewed literature

 

You have (Requirements) 

• You will have excellent attention to details, strong communication skills and be able to interact with technical experts as well as scientists seeking solutions to their “real world” problems.
• A PhD (or equivalent) in a biological or biomedical science
• Excellent knowledge of pharmacology, potential biological targets and mechanisms of drug action
• Good knowledge of the various experimental techniques used to determine the activity of compounds in different in vitro and in vivo assay systems
• Ability to work accurately and quickly to deadlines
• Able to work both as part of a team and independently
• Good communication skills (both verbal and presentational)   

 

You might also have (Desirable)

• Prior experience of biological data curation and knowledge of bioinformatics databases
• Some knowledge of biological ontologies
• Experience of working in a drug discovery environment
• Experience of working with and manipulating file formats such as FASTA, Excel, XML, OBO and familiarity with regular expressions and text matching
• Experience of querying relational databases using SQL would also be advantageous

 

Our ideal candidate embraces:

• Open mindset – welcoming diverse ideas and perspectives.
• Professional outlook – ensuring meticulous attention to quality and detail.
• Teamwork – working together for shared success.
• Respect – treating all colleagues with professionalism and kindness
• Inclusivity – allowing everyone space to shine in their own way.