The climate crisis cannot be addressed in isolation. It is inseparable from biodiversity loss, water scarcity, food insecurity, pollution, and other global problems. This was the central message from the Intergovernmental Science-Policy Platform on Biodiversity and Ecosystem Services (IPBES) Nexus Assessment, approved by Member Governments in December 2024, which we co-chaired over three years. The assessment highlights that the world is facing interlinked crises that amplify one another, and that tackling them in separate silos has been ineffective and even counterproductive. Yet the Nexus Assessment also provides clear evidence and tools for a wide range of integrated response options that are available now for tackling these crises together.