Assessing the impacts of unprecedented biodiversity loss on planetary resilience, The Economics of Biodiversity: the Dasgupta Review (“Dasgupta Review”) asserts that sustainable engagement with nature is crucial for sustaining the livelihoods of present and future generations. It further urges the integration of biodiversity into national accounting and science-based decision-making processes in order to advance the well-being of both people and the planet. Here, we present the salient features of the Dasgupta Review along with several recommendations for strengthening global biodiversity and ecosystem conservation efforts. Although institutional transformations at regional and national scales are essential to facilitate the recognition of economies’ dependence on nature, behavioral changes at the level of the individual are also needed to better understand, value, manage, and utilize biodiversity. Formulation of inclusive policies prioritizing biodiversity conservation and sustainable resource consumption is also essential for averting future public health risks associated with ecosystem degradation and species loss.