The identification of the main steps for the creation of a unified ecosystem from the institutional point of view and the framework for ecosystem design is presented and discussed. Based on the expertise and the knowledge gained during the time when the ELISE project had been implemented, a unified Kaunas city ecosystem is being designed using the Ecosystem Map method. As the review of the ELISE project reports helped to identify the main steps of each project partner in building ecosystems’ networks, Kaunas city chose to create a co-Creation Hub (c-CH), which is the first step in developing an ecosystem management model. The main tasks of such a hub are listed and should involve the preparation of a long-term action plan involving not only the coordination of the stakeholder meetings, organization of seminars, the preparation of new materials, and methodology but also the development of a clear strategy for each stakeholder based on the national economy and government and municipality policies. The role of the c-CH is to ensure the ease of cooperation and knowledge distribution among stakeholders within the city, public authorities, and the national government. This approach could become a fundamental background tool for the regional and/or city municipal and stakeholder-based creation and development of unified ecosystem development.