When EPA registers a pesticide or reevaluates it in registration review, the Agency has a responsibility under the Endangered Species Act (ESA) to ensure that the pesticide registrations do not jeopardize the continued existence of federally threatened or endangered (listed) species or adversely modify their designated critical habitats. Chemical stressors, such as pesticides, are one of many factors that can contribute to population declines of listed species. Other factors include habitat loss, climate change, invasive species, and pests/diseases. In April 2022, EPA released its workplan to address the complexity of meeting its ESA obligations for actions taken under the Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA). This comprehensive workplan establishes four overall strategies and dozens of actions that EPA will adopt, in collaboration with other federal agencies, to improve protection for federally threatened and endangered (listed) species and meet our ESA obligations. Subsequently, in November 2022, EPA issued a workplan update that describes several current and future programmatic initiatives with other federal agencies to prioritize mitigation for listed species that are particularly vulnerable to pesticides and to improve the efficiency and timeliness of the ESA-FIFRA process.